Page Cannot Be Found - 404 2 1260

When you got this error 'Page cannot be found' on IIS 6
Resolution is to enable ISAPI and CGI on Web Service Extension folder in IIS.
Reference: here

How do you know that error number 404 2 1260?
It's from the Log files, usually located at C:\Windows\System32\LogFiles\
can be found from the following step:
Go to your website properties -> On 'Web Sites' tab, click the 'Properties ...'
There's Log File name field above the buttons.
The for Default web site will be W3SCV1

From the log files u can see the logs of your IIS website.